Original Paper
Authors
Keywords
ozono
compuestos ozonizados
aceites vegetales
aceites ozonizados
Abstract
Early evidence on the clinical use of ozonated oils first appear in scientific literature in 1859. This paper reviews the general and main clinical applications of ozonated oils that have appeared in scientific literature between 1859-2011. The oxidation products
generated after the reaction of ozone with fatty acids and other substrates can acts as a germicide, immune stimulantand tissue restoration agent. The biological activities and stability of the ozonated oilsallows the development of standard formulations that
deliver the benefits of ozone, supported by pre-clinical and clinical studies.The main clinical studies that support the use of ozonized oils apply ozonizedsunflower oil orozonizedolive oil in different clinical conditions. The applications are essentially for
external use, however there is evidence of immune-stimulating and repaireffects when used orally. A deep study of the biological effects of various formulations already on the market will support the scientific basis of the use of ozonized oil in different pathologies.
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