Bibliographic review


Basil Ribeiro


The alteration in the balance between reactive oxygen species (ROS) generation and antioxidant buffering capacity creates oxidative stress in the body that leads to disease on the body systems. The ROS are the operating agents to create an oxidative state of the body. There are biological mechanisms to tamper these agents and to reach a redox equilibrium, for promotion of health and avoid sickness. Some mechanisms of the oxidative stress will be discussed on the paper. The glutathione is a tripeptide, it the first line of defence against oxidative damage, being very important for the protection of the cells from oxidative damage and maintaining redox homeostasis. The synthesis, the function, the consequences of the depletion and the supplementation of glutathione will be presented. The contribution of phytochemicals as antioxidants will be briefly discussed and examples of useful plants will be presented


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