Original paper
Author
Juan Carlos Crespo, Sandro Argüelles, Mario F. Muñoz, Eugenio Velasco, Miguel Muñoz, Cristina Garzón-Rodriguez, Antonio Ayala
Abstract
Ozone has many therapeutic effects. The mechanism of action of ozone therapy lays mainly in several aspects, being one of them the stimulation of tissue healing. In this work, we have carried out a preliminary study of the possible effect of ozone on the regeneration capacity of tissues. For this, we have studied the effect of ozone on neurokinin 1 receptor (NK1R) levels in mesenchymal stem cells of adipose tissue. NK1R are the cellular receptors of substance P both are involved in cellular proliferation. The results show that ozone specifically increases the expression of NK1R in stem cells but not in cancer cells
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